Sleepiness often improves with modafinil, armodafinil, amphetamines, or sodium oxybate. See Narcolepsy: NHS Choices and the EFNS guidelines on management of narcolepsy (Billiard et al. Medications are a core therapy for most people with narcolepsy. Many of these medicines are not licensed for the treatment of narcolepsy and they vary in the evidence available for their effectiveness in treating narcolepsy. These include stimulants such as modafinil, dexamfetamine or methylphenidate sodium oxybate or antidepressants such as selective serotonin reuptake inhibitors (SSRIs), serotonin–noradrenaline reuptake inhibitors (SNRIs) or tricyclic antidepressants. Several medicines are used to treat the symptoms of narcolepsy. Accessing counselling and support may also be important for people to come to terms with the sleep disorder and its implications. ![]() The specific disorders included in these practice parameters are narcolepsy (with cata- plexy, without cataplexy. Managing narcolepsy involves implementing good sleep hygiene, which may include taking brief planned naps and sticking to a strict bedtime routine. ten represent the primary mode of therapy. Sleep paralysis: a temporary inability to move or speak when waking up or falling asleepĮxcessive dreaming: dreams often come when falling asleep (hypnogogic hallucinations) or just before or during waking (hypnopompic hallucinations)ĭisturbed nocturnal sleep: frequent waking in the night. ![]() These medications are very effective but can be addictive. Some people need treatment with methylphenidate (Aptensio XR, Concerta, Ritalin, others) or various amphetamines. Pitolisant may also be helpful for cataplexy. ![]() Sleep attacks: falling asleep suddenly and without warningĬataplexy: temporary loss of muscle control resulting in weakness and possible collapse, often in response to emotions such as laughter and anger Sunosi (solriamfetol) and pitolisant (Wakix) are newer stimulants used for narcolepsy, headache and anxiety. Excessive daytime sleepiness: feeling very sleepy throughout the day, and having difficulty concentrating and staying awake
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